Description

5-Bromo-2-(Ethylthio)Pyridine is a versatile brominated heterocyclic building block featuring a pyridine core substituted with bromine and an ethylthio group. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecules through cross-coupling reactions. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• As a key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small-molecule therapeutics.
• Utilized as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Employed in agrochemical research for the development of novel herbicides, fungicides, and insecticides.
• Serves as a precursor for ligand synthesis in catalysis and material science applications.
• Used in organic electronic materials research for the construction of functionalized heterocyclic components.

Basic Information

Item	Detail
Product Name	5-Bromo-2-(Ethylthio)Pyridine
CAS No.	127800-66-2
Molecular Formula	C7H8BrNS
Molecular Weight	218.11 g/mol
Synonyms	2-(Ethylthio)-5-bromopyridine; 5-Bromo-2-ethylsulfanylpyridine; 5-Bromo-2-(ethylmercapto)pyridine; 5-Bromo-2-ethylthiopyridine; 2-Ethylthio-5-bromopyridine; 5-Bromo-2-ethylsulfanyl-pyridine; 5-Bromo-2-(ethylthio)pyridine; 5-Bromo-2-ethylsulfanylpyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Ethylthio)Pyridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.