Description

(2S)-2-[[(Benzyloxy)Carbonyl]Amino]-5-Hexenoic Acid tert-Butyl Ester is a high-purity, chiral amino acid derivative designed for advanced synthetic chemistry. This compound serves as a critical, protected building block for the controlled synthesis of complex peptides and peptidomimetics. It is essential for researchers and manufacturers in pharmaceutical development, particularly in the creation of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid derivative for the controlled elongation of peptide chains.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of novel pharmacophores.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins via its reactive terminal alkene handle.
• Combinatorial Chemistry: Serves as a versatile building block in libraries for high-throughput screening.
• Asymmetric Synthesis: Utilized in catalytic reactions to introduce stereogenic centers with high enantiomeric purity.

Basic Information

Product Name	(2S)-2-[[(Benzyloxy)Carbonyl]Amino]-5-Hexenoic Acid tert-Butyl Ester
CAS No.	127623-77-2
Molecular Formula	C19H27NO4
Molecular Weight	333.43 g/mol
Synonyms	N-Cbz-L-2-Amino-5-hexenoic acid tert-butyl ester; (S)-tert-Butyl 2-(((benzyloxy)carbonyl)amino)hex-5-enoate; Boc-L-2-Amino-5-hexenoic acid OBzl derivative; Z-L-2-Amino-5-hexenoic acid O-t-butyl ester; Nα-Cbz-L-2,4-Diaminobutanoic acid 5-ene tert-butyl ester; L-2-Amino-5-hexenoic acid, N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester; (2S)-2-[(Benzyloxycarbonyl)amino]-5-hexenoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (2S)-2-[[(Benzyloxy)Carbonyl]Amino]-5-Hexenoic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The compound is light-sensitive and should be handled and stored away from strong acids and organic solvents to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.