Description

Ethyl 7-Bromo-4-Chloro-1,5-Naphthyridine-3-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering precise reactivity for complex molecular construction. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated naphthyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic libraries in combinatorial chemistry and for exploring new chemical entities.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, ligands for catalysts, and advanced polymers requiring specific aromatic architectures.

Basic Information

Item	Detail
Product Name	Ethyl 7-Bromo-4-Chloro-1,5-Naphthyridine-3-Carboxylate
CAS No.	127448-21-9
Molecular Formula	C11H8BrClN2O2
Molecular Weight	315.55 g/mol
Synonyms	7-Bromo-4-chloro-1,5-naphthyridine-3-carboxylic acid ethyl ester; Ethyl 7-bromo-4-chloro-1,5-naphthyridine-3-carboxylate; 1,5-Naphthyridine-3-carboxylic acid, 7-bromo-4-chloro-, ethyl ester; 127448-21-9; 7-Bromo-4-chloro-1,5-naphthyridine-3-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-Bromo-4-Chloro-1,5-Naphthyridine-3-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to guarantee batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.