Description

Decarestrictine B CAS NO 127393-91-3 is a specialized, high-purity secondary metabolite of significant interest in advanced pharmaceutical research and development. This compound matters for its potent biological activity, serving as a key intermediate and reference standard in the discovery of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in metabolic pathway studies, oncology research, and the synthesis of complex natural product derivatives.

Application

• Pharmaceutical R&D Intermediate: A critical building block in the synthesis of novel drug candidates targeting specific cellular pathways.
• Biological Reference Standard: Used for analytical method development, validation, and quality control in bioassay systems.
• Metabolic Research: Employed in studies investigating enzyme inhibition and the regulation of metabolic processes.
• Oncology and Cell Biology Studies: Serves as a tool compound for probing mechanisms of action in cancer cell lines and other biological models.
• Natural Product Chemistry: Used as a benchmark in the isolation, characterization, and synthetic recreation of complex natural products.
• High-Throughput Screening (HTS): Incorporated into compound libraries for the discovery of new bioactive molecules.

Basic Information

Product Name	Decarestrictine B
CAS No.	127393-91-3
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	Decarestrictine B; (3R,4S,5S,6R)-6-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one; 2H-Pyran-2-one, 6-(1,2-dihydroxyethyl)tetrahydro-4,5-dihydroxy-, (3R,4S,5S,6R)-; Decarestrictine B1 (related); Microbial metabolite with HMG-CoA reductase inhibitory activity.
EINECS	Contact for details

Quality Control

Our Decarestrictine B is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material at 2-8°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.