Description

Zamifenacin is a selective muscarinic M3 receptor antagonist with significant pharmacological activity. This compound is a key intermediate and active pharmaceutical ingredient (API) in the research and development of novel therapeutic agents targeting smooth muscle disorders. It is primarily utilized by pharmaceutical R&D laboratories and manufacturers engaged in the synthesis of advanced drug candidates for urological and gastrointestinal conditions.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of muscarinic receptor antagonist drugs.
• Research & Development: Used in preclinical and clinical research to study M3 receptor pharmacology and develop new therapeutic entities.
• Active Pharmaceutical Ingredient (API): Employed in the formulation development of final drug products targeting overactive bladder and irritable bowel syndrome.
• Reference Standard: Acts as a high-purity chemical standard for analytical method development and quality control in pharmaceutical manufacturing.
• Biochemical Research: Utilized in studies investigating cholinergic signaling pathways and receptor-ligand interactions.

Basic Information

Item	Detail
Product Name	Zamifenacin
CAS No.	127308-82-1
Molecular Formula	C23H26N2O3S
Molecular Weight	410.53 g/mol
Synonyms	Zamifenacin; UK-76654; (R)-3-(Diphenylmethoxy)-1-(3,4-dimethoxyphenethyl)piperidine; (3R)-3-(Diphenylmethoxy)-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidine; 1-(3,4-Dimethoxyphenethyl)-3-diphenylmethoxypiperidine; (R)-Zamifenacin; UK 76654; Zamifenacinum
EINECS	Contact for details

Quality Control

Our Zamifenacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, confirming compliance with in-house specifications developed for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.