Description

1,1'-Dioctadecyl-3,3,3',3'-Tetramethylindodicarbocyanine Perchlorate is a lipophilic, near-infrared (NIR) fluorescent cyanine dye widely used as a membrane probe and labeling reagent in advanced life science research. Its exceptional photostability, high molar absorptivity, and strong fluorescence quantum yield in hydrophobic environments make it ideal for long-term cellular imaging and lipid bilayer studies. This compound is essential for researchers and manufacturers in biotechnology, pharmaceutical development, and diagnostic assay design who require precise, reproducible NIR fluorescence performance under demanding experimental conditions.

Application

• Fluorescent labeling of cell membranes and lipid rafts in live-cell NIR microscopy
• Tracing membrane fusion and endocytosis dynamics in real time
• Development of NIR-based in vitro diagnostic kits (e.g., lateral flow assays with enhanced sensitivity)
• Reference standard and calibration material for fluorescence spectrophotometry and imaging system validation
• Component in optoacoustic contrast agents for preclinical small-animal imaging
• Surface functionalization of liposomal drug delivery systems for biodistribution tracking
• Research-grade reagent for Förster resonance energy transfer (FRET) pair construction in membrane protein studies
• Quality control standard in GMP-compliant manufacturing of fluorescent bioconjugates

Basic Information

Product Name	1,1'-Dioctadecyl-3,3,3',3'-Tetramethylindodicarbocyanine Perchlorate
CAS No.	127274-91-3
Molecular Formula	C65H98ClN4O4
Molecular Weight	1051.97 g/mol
Synonyms	DiI-C18(3); DID; 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindodicarbocyanine perchlorate; DiIC18(3); 3,3'-Di(1-octadecyl)-5,5'-bis(4-sulfobutyl)indodicarbocyanine; DiIC18(5); 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindodicarbocyanine; DIC18; DiIC18(3) perchlorate; Indodicarbocyanine, 1,1'-dioctadecyl-3,3,3',3'-tetramethyl-, perchlorate
EINECS	Not listed (not assigned)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are tested for identity (IR, HPLC retention time), purity (≥95.0% by HPLC), moisture content (≤0.5% by Karl Fischer), and perchlorate salt integrity. Testing follows ACS Reagent Grade and ISO/IEC 17025–compliant protocols to guarantee batch-to-batch consistency and suitability for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8°C under inert atmosphere (argon or nitrogen) to prevent oxidation and moisture uptake. Due to its hygroscopic nature, minimize exposure to ambient humidity during handling. Keep away from direct sunlight and UV sources at all times.

Specification

Item	Specification
Appearance	Purple-black crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥95.0%
Moisture (Karl Fischer)	≤0.5%
Residue on Ignition	≤0.1%
Solubility	Soluble in chloroform, DMSO, methanol; sparingly soluble in water
Absorption λmax (in chloroform)	645–655 nm
Fluorescence λem (in chloroform)	660–670 nm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.