Description

(9-Fluorenylmethyl)Ethylcarbonate CAS NO 127228-99-3 is a specialized carbamate derivative of 9-fluorenylmethanol, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile protecting group for amines and alcohols, particularly in the synthesis of complex peptides, nucleotides, and pharmaceuticals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for sensitive multi-step syntheses.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Used as a protecting group (Fmoc-group precursor) for amino acids during solid-phase and solution-phase peptide synthesis.
• Nucleotide Chemistry: Employed in the protection of nucleosides and nucleotides during oligonucleotide synthesis for research and therapeutic applications.
• Fine Chemical Production: Serves as a reagent for introducing the fluorenylmethyloxycarbonyl (Fmoc) protecting group in custom synthesis and process chemistry.
• Academic & Industrial Research: A valuable tool compound for methodological development in organic chemistry and material science laboratories.
• Agrochemical Synthesis: Intermediate in the development of advanced crop protection agents and specialty agrochemicals.

Basic Information

Product Name	(9-Fluorenylmethyl)Ethylcarbonate
CAS No.	127228-99-3
Molecular Formula	C₁₇H₁₆O₃
Molecular Weight	268.31 g/mol
Synonyms	9-Fluorenylmethyl ethyl carbonate; Ethyl (9H-fluoren-9-yl)methyl carbonate; Fmoc-OEt; N-(9-Fluorenylmethoxycarbonyloxy)ethane; 9-Fluorenylmethyloxycarbonyl ethyl ester; Ethyl fluoren-9-ylmethoxyformate; 9-Fmoc ethyl carbonate; 9H-Fluoren-9-ylmethyl ethyl carbonate
EINECS	Contact for details

Quality Control

Our (9-Fluorenylmethyl)Ethylcarbonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Quality is verified against in-house specifications developed for research and process chemistry use. For specific regulatory requirements, including cGMP or other standards, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.