Description

Piperidin-2-Ylmethyl Trifluoromethanesulfonate is a high-purity triflate ester derivative of a piperidine scaffold, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile alkylating agent and a protected intermediate for introducing the piperidin-2-ylmethyl moiety into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, especially those targeting neurological disorders and as modulators of biological receptors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the piperidine moiety for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein interactions.
• Material Science Research: Potential monomer or functionalization agent in the development of advanced polymers with specific chemical properties.
• Custom Synthesis and Scale-up: A critical reagent for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	Piperidin-2-Ylmethyl Trifluoromethanesulfonate
CAS No.	127075-48-3
Molecular Formula	C8H14F3NO3S
Molecular Weight	261.26 g/mol
Synonyms	2-Piperidinylmethyl Triflate; (Piperidin-2-yl)methyl Trifluoromethanesulfonate; Trifluoromethanesulfonic Acid Piperidin-2-Ylmethyl Ester; 2-(Trifluoromethanesulfonyloxymethyl)piperidine; 1,2,3,6-Tetrahydropyridine-2-methyl Triflate; Piperidine-2-methanol Triflate; Piperidin-2-ylmethanol Triflate Ester
EINECS	Contact for details

Quality Control

Every batch of Piperidin-2-Ylmethyl Trifluoromethanesulfonate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its sensitivity, the container should be kept tightly sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.