Description

(2E)-1-Phenyl-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One is a high-purity synthetic chalcone derivative, a key chemical scaffold valued for its biological activity and utility in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a reliable, well-characterized building block for pharmaceutical and agrochemical development. It serves as a critical intermediate for medicinal chemistry programs targeting anti-inflammatory, anticancer, and antimicrobial agents.

Application

• Pharmaceutical Intermediate: Core scaffold for the research and synthesis of novel drug candidates with potential anti-inflammatory, anticancer, and antimicrobial properties.
• Medicinal Chemistry Research: Key building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Development: Intermediate in the synthesis of new crop protection agents and bioactive molecules.
• Chemical Biology: Probe molecule for studying biological pathways and protein interactions.
• Organic Synthesis: Versatile starting material for synthesizing more complex heterocyclic compounds and fine chemicals.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	(2E)-1-Phenyl-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One
CAS No.	127034-55-3
Molecular Formula	C18H18O4
Molecular Weight	298.33 g/mol
Synonyms	(E)-1-Phenyl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one; (E)-3-(3,4,5-Trimethoxyphenyl)-1-phenylprop-2-en-1-one; 3,4,5-Trimethoxychalcone; NSC 407296; Chalcone, 3,4,5-trimethoxy-; 2-Propen-1-one, 1-phenyl-3-(3,4,5-trimethoxyphenyl)-, (2E)-; 3',4',5'-Trimethoxychalcone
EINECS	Contact for details

Quality Control

Our (2E)-1-Phenyl-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR, MS). We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.