Description

4-(tert-Butyl-Dimethyl-Silanyloxy)-Cyclohexanol is a protected cyclohexanol derivative, where the hydroxyl group is shielded by a tert-butyldimethylsilyl (TBDMS) group. This protection is crucial for its role as a versatile synthetic intermediate in advanced organic synthesis, offering enhanced stability and selectivity during complex chemical transformations. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used as a protected alcohol synthon in complex organic reactions, including cross-coupling and chiral synthesis.
• Agrochemical Research: Serves as an intermediate in the development of novel pesticides, herbicides, and plant growth regulators.
• Material Science: Employed in the research and production of specialty polymers, liquid crystals, and advanced organic materials.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in university and corporate research laboratories.

Basic Information

Product Name	4-(tert-Butyl-Dimethyl-Silanyloxy)-Cyclohexanol
CAS No.	126931-29-1
Molecular Formula	C₁₂H₂₆O₂Si
Molecular Weight	230.42 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]cyclohexanol; 4-(TBDMS-oxy)cyclohexanol; trans-4-(tert-Butyldimethylsiloxy)cyclohexanol; 4-(tert-Butyldimethylsilyloxy)cyclohexanol; 4-Hydroxycyclohexyloxy-tert-butyldimethylsilane; Cyclohexanol, 4-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol; 4-TBDMSO-cyclohexanol
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyl-Dimethyl-Silanyloxy)-Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.