Description

Spiro[2.4]Hepta-4,6-Diene-1-Carboxaldehyde, 2,2-Dimethyl-, (R)- (9Ci) is a high-value, chiral spirocyclic building block with a defined stereocenter, identified by CAS number 126899-49-8. This compound is prized for its unique rigid structure and aldehyde functionality, which are critical for constructing complex molecular architectures in advanced synthetic chemistry. It serves as a key chiral intermediate for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its spirocyclic core can contribute to unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials that require specific, rigid molecular geometries.
• Academic and R&D Laboratories: A valuable tool for methodological studies in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Product Name	Spiro[2.4]Hepta-4,6-Diene-1-Carboxaldehyde, 2,2-Dimethyl-, (R)- (9Ci)
CAS No.	126899-49-8
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	(R)-2,2-Dimethylspiro[2.4]hepta-4,6-diene-1-carboxaldehyde; (R)-2,2-Dimethyl-1-spiro[2.4]hepta-4,6-dienecarboxaldehyde; (R)-2,2-Dimethylspiro[2.4]hepta-4,6-diene-1-carbaldehyde; (R)-2,2-Dimethyl-1-formylspiro[2.4]hepta-4,6-diene; (R)-Spirobicyclo[2.2.1]hept-5-ene-2,2-dimethylethanal (related); (R)-Chiral Spiro Aldehyde; 126899-49-8
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through advanced analytical techniques including Chiral HPLC for enantiomeric excess (ee) determination, GC/HPLC for chemical purity, and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.