Description

Ethyl 2-[Benzyloxycarbonylimino]-3,3,3-Trifluoro-Propionate is a specialized fluorinated organic building block of significant interest in advanced synthetic chemistry. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly those incorporating the pharmacologically relevant trifluoromethyl group. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients. The unique combination of the benzyloxycarbonyl protecting group and the trifluoromethyl moiety makes it a versatile reagent for constructing peptidomimetics and other bioactive scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially protease inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the trifluoromethyl group enhances biological activity and stability.
• Peptidomimetic Synthesis: Serves as a protected amino acid derivative for constructing modified peptides and peptide-like compounds in medicinal chemistry.
• Fluorine Chemistry: An essential reagent for introducing the CF3 group into complex molecular architectures in academic and industrial R&D.
• Material Science Precursor: Potential use in creating specialty polymers and advanced materials with unique surface properties.

Basic Information

Product Name	Ethyl 2-[Benzyloxycarbonylimino]-3,3,3-Trifluoro-Propionate
CAS No.	126535-92-0
Molecular Formula	C13H12F3NO4
Molecular Weight	303.24 g/mol
Synonyms	Ethyl 2-[(Benzyloxy)carbonylimino]-3,3,3-trifluoropropanoate; Z-NH=C(CF3)COOEt; N-(Benzyloxycarbonyl)-3,3,3-trifluoro-2-iminopropanoic Acid Ethyl Ester; Ethyl 3,3,3-Trifluoro-2-[(phenylmethoxy)carbonylimino]propanoate; 2-[(Benzyloxycarbonyl)imino]-3,3,3-trifluoropropionic Acid Ethyl Ester; N-Cbz-3,3,3-trifluoro-2-iminopropionate Ethyl Ester; Ethyl N-Cbz-trifluoropyruvate imine
EINECS	Contact for details

Quality Control

Our Ethyl 2-[Benzyloxycarbonylimino]-3,3,3-Trifluoro-Propionate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity (typically >95% by HPLC), identity confirmation, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.