Description

Ethyl 2-[tert-Butoxycarbonylimino]-3,3,3-Trifluoro-Propionate is a high-value, specialty fluorinated building block used in advanced organic synthesis. This compound is critical for introducing the trifluoromethyl group and protected imino functionality into target molecules, enabling the development of compounds with enhanced metabolic stability and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used to construct advanced intermediates for novel herbicides and pesticides that leverage fluorine's unique properties.
• Peptidomimetics Research: Serves as a protected amino acid derivative for constructing fluorinated peptide analogs in medicinal chemistry.
• Material Science: Potential building block for specialty polymers and advanced materials requiring fluorinated components.
• Chemical Biology Probes: Employed in the development of labeled compounds and probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific, high-value intermediates under cGMP conditions where required.

Basic Information

Product Name	Ethyl 2-[tert-Butoxycarbonylimino]-3,3,3-Trifluoro-Propionate
CAS No.	126535-90-8
Molecular Formula	C10H14F3NO4
Molecular Weight	269.22 g/mol
Synonyms	Ethyl 2-[(tert-Butoxycarbonyl)imino]-3,3,3-trifluoropropanoate; Ethyl 3,3,3-Trifluoro-2-[(2-methyl-2-propanyloxycarbonyl)imino]propanoate; N-Boc-3,3,3-Trifluoroalanine Ethyl Ester Imino Derivative; 2-[(tert-Butoxycarbonyl)imino]-3,3,3-trifluoropropionic Acid Ethyl Ester; Boc-NH=C(CF3)COOEt; Ethyl 2-(Boc-imino)-3,3,3-trifluoropropionate; 3,3,3-Trifluoro-2-[(2-methylpropan-2-yl)oxycarbonylimino]propanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-[tert-Butoxycarbonylimino]-3,3,3-Trifluoro-Propionate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production can align with cGMP guidelines for pharmaceutical applications upon request, ensuring supply chain integrity for advanced R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.