Description

1,4-Dioxa-8-Azaspiro[4.5]Decane-8-Carboxylic Acid, 7-Methyl-, 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. Its spirocyclic structure and acid-labile tert-butyloxycarbonyl (Boc) protecting group make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of complex drug candidates, including protease inhibitors and other small molecule therapeutics.
• Peptide & Peptidomimetic Chemistry: Used as a protected amino acid analog in solid-phase and solution-phase peptide synthesis to introduce conformational constraints.
• Agrochemical Research: Building block for creating novel pesticides and herbicides with specific biological activity.
• Ligand & Catalyst Development: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate in the production of specialty polymers and functional materials requiring specific molecular recognition sites.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	1,4-Dioxa-8-Azaspiro[4.5]Decane-8-Carboxylic Acid, 7-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	126503-08-0
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	tert-Butyl 7-methyl-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxylate; Boc-7-methyl-1,4-dioxa-8-azaspiro[4.5]decane; 8-Boc-7-methyl-1,4-dioxa-8-azaspiro[4.5]decane; (7-Methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 7-methyl-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxylate; 7-Methyl-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; Protected spirocyclic amino ester; Boc-protected spirocyclic proline analog
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxa-8-Azaspiro[4.5]Decane-8-Carboxylic Acid, 7-Methyl-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.