Description

1'H-Spiro[Cyclohexane-1,2'-Quinazoline]-4'-Thiol is a specialized spirocyclic organic compound featuring a quinazoline-thiol moiety, serving as a valuable synthetic intermediate and building block in advanced chemical research. Its unique fused ring structure makes it a critical precursor for developing novel heterocyclic compounds with potential biological activity. This high-purity material is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on medicinal chemistry and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for creating specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Synthesis: Employed in heterocyclic and spirocyclic chemistry to construct complex molecular architectures for research and development.
• Bioconjugation & Probe Development: The thiol group allows for site-specific conjugation, useful in creating biochemical probes and labeled compounds.

Basic Information

Product Name	1'H-Spiro[Cyclohexane-1,2'-Quinazoline]-4'-Thiol
CAS No.	126492-23-7
Molecular Formula	C₁₃H₁₆N₂S
Molecular Weight	232.34 g/mol
Synonyms	1'H-Spiro[cyclohexane-1,2'-quinazoline]-4'-thiol; 4'-Thio-1'H-spiro[cyclohexane-1,2'-quinazoline]; Spiro[cyclohexane-1,2'-quinazoline]-4'-thiol; 1'H-Spiro(cyclohexane-1,2'-quinazoline)-4'-thiol; 126492-23-7; Quinazoline-4'-thiol, 1'H-spiro[cyclohexane-1,2']-
EINECS	Contact for details

Quality Control

Our 1'H-Spiro[Cyclohexane-1,2'-Quinazoline]-4'-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.