Description

(E)-4,4'-Dibromochalcone CAS NO 126443-21-8 is a high-purity, synthetic organic compound belonging to the chalcone class, characterized by its distinct (E)-configuration and bromine substituents. This compound serves as a versatile and valuable pharmaceutical intermediate and organic building block for advanced chemical synthesis. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammatory and oncological pathways.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Heck) and cyclization reactions to construct complex heterocyclic compounds.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with enhanced efficacy.
• Material Science: Investigated as a monomer or additive for creating specialized polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in research to study biological processes and protein interactions due to its specific structural motif.
• Academic & Industrial R&D: Employed in discovery chemistry for creating libraries of novel compounds for screening.

Basic Information

Product Name	(E)-4,4'-Dibromochalcone
CAS No.	126443-21-8
Molecular Formula	C15H10Br2O
Molecular Weight	366.05 g/mol
Synonyms	(E)-1,3-Diphenyl-2-propen-1-one, 4,4'-Dibromo Derivative; 4,4'-Dibromochalcone; (E)-3-(4-Bromophenyl)-1-(4-bromophenyl)prop-2-en-1-one; 1,3-Bis(4-bromophenyl)-2-propen-1-one; trans-4,4'-Dibromochalcone; Chalcone, 4,4'-dibromo-; NSC 407296
EINECS	Contact for details

Quality Control

Our (E)-4,4'-Dibromochalcone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.