Description

n-Methylallyldimethylsilyltrifluoroacetic Acid CAS NO 126235-52-7 is a specialized organosilicon reagent featuring a reactive trifluoroacetate group and a protected allyl functionality. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly for introducing silicon-protected moieties under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of complex molecules and novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring silicon-based protecting groups or fluorinated segments.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its unique structure can contribute to biological activity and metabolic stability.
• Polymer & Material Science: Acts as a monomer or functionalization agent in the creation of specialty silicones, fluorinated polymers, and advanced materials with tailored surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cross-coupling reactions, nucleophilic substitutions, and as a precursor to other functionalized silanes.
• Ligand & Catalyst Development: Useful in the preparation of novel organosilicon ligands for transition metal catalysis.

Basic Information

Product Name	n-Methylallyldimethylsilyltrifluoroacetic Acid
CAS No.	126235-52-7
Molecular Formula	C8H13F3O2Si
Molecular Weight	226.27 g/mol
Synonyms	2-(Dimethyl(methylallylsilyl)oxy)-2,2-difluoroacetic acid; Trifluoroacetic acid 2-(dimethyl(methyl-2-propenylsilyl)) ester; (Methylallyldimethylsilyl) trifluoroacetate; Allyldimethyl(methyl)silyl trifluoroacetate; 1,1,1-Trifluoro-2-[(methylallyldimethylsilyl)oxy]ethanone
EINECS	Contact for details

Quality Control

Our n-Methylallyldimethylsilyltrifluoroacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.