Description

4,5,6,7-Tetrahydro-5-Methylimidazo(4,5,1-Jk)(1,4)Benzodiazepin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the benzodiazepine class. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is essential for pharmaceutical manufacturers and R&D laboratories focused on developing new active pharmaceutical ingredients (APIs) with potential neurological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Neurological Drug Development: Serves as a precursor for compounds being investigated for potential effects on the central nervous system.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for pharmacological and biochemical studies.

Basic Information

Product Name	4,5,6,7-Tetrahydro-5-Methylimidazo(4,5,1-Jk)(1,4)Benzodiazepin-2(1H)-One
CAS No.	126233-79-2
Molecular Formula	C12H13N3O
Molecular Weight	215.25 g/mol
Synonyms	5-Methyl-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one; 5-Methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5,1-jk][1,4]benzodiazepin-2-one; Imidazo-benzodiazepinone derivative; 126233-79-2; Tetrahydroimidazobenzodiazepinone
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydro-5-Methylimidazo(4,5,1-Jk)(1,4)Benzodiazepin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.