Description

8-(4-Bromophenyl)-1,4-Dioxaspiro[4.5]decan-8-ol is a high-value brominated spirocyclic compound featuring a protected ketone group, serving as a versatile and critical synthetic intermediate. Its unique structure makes it essential for constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with spirocyclic motifs.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals due to its rigid, brominated aromatic structure.
• Organic Synthesis: Versatile intermediate for constructing complex natural product analogs and other spirocyclic compounds via further functionalization.
• Chemical Biology: Utilized in the development of molecular probes and tags for biochemical research.

Basic Information

Product Name	8-(4-Bromophenyl)-1,4-Dioxaspiro[4.5]decan-8-ol
CAS No.	125962-59-6
Molecular Formula	C15H19BrO3
Molecular Weight	327.22 g/mol
Synonyms	8-(4-Bromophenyl)-1,4-dioxaspiro[4.5]decan-8-ol; 8-(p-Bromophenyl)-1,4-dioxaspiro[4.5]decan-8-ol; 8-(4-Bromophenyl)-8-hydroxy-1,4-dioxaspiro[4.5]decane; 4-Bromophenyl spirocyclic ketal alcohol; 1,4-Dioxaspiro[4.5]decan-8-ol, 8-(4-bromophenyl)-; Bromophenyl dioxaspirodecanol
EINECS	Contact for details

Quality Control

Our 8-(4-Bromophenyl)-1,4-Dioxaspiro[4.5]decan-8-ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.