Description

Boc-3-Iodo-D-Alanine Benzyl Ester is a protected, non-natural amino acid derivative of significant value in advanced organic synthesis. This compound is specifically engineered to serve as a key chiral building block for the construction of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic probes, and bioactive molecules, where precise stereochemistry and functional group manipulation are critical.

Application

• Peptide Synthesis: A crucial chiral intermediate for the solid-phase and solution-phase synthesis of custom peptides containing iodinated tyrosine or alanine analogs.
• Pharmaceutical Research: Used in the discovery and development of novel drug candidates, particularly in creating targeted radiopharmaceuticals and molecular imaging probes due to the iodine atom.
• Chemical Biology: Employed for the site-specific incorporation of iodine labels into proteins and peptides for structural studies, binding assays, and tracking applications.
• Library Synthesis: A valuable building block for generating diverse combinatorial libraries of small molecules and peptides for high-throughput screening.
• Agrochemical Development: Can be used in the synthesis of bioactive compounds with potential applications in crop protection.
• Academic Research: Serves as a specialized reagent in university and institutional labs for methodological development in asymmetric synthesis and organoiodine chemistry.

Basic Information

Item	Detail
Product Name	Boc-3-Iodo-D-Alanine Benzyl Ester
CAS No.	125942-79-2
Molecular Formula	C15H20INO4
Molecular Weight	405.23 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-(3-iodophenyl)propanoic acid benzyl ester; Boc-D-3-Iodophenylalanine benzyl ester; N-(tert-Butoxycarbonyl)-3-iodo-D-phenylalanine benzyl ester; Boc-3-Iodo-D-Phe-OBzl; tert-Butyl (R)-(1-benzyloxy-1-oxo-3-(3-iodophenyl)propan-2-yl)carbamate
EINECS	Contact for details

Quality Control

Every batch of Boc-3-Iodo-D-Alanine Benzyl Ester is produced and tested under strict quality management protocols to ensure high chemical purity and chiral integrity. Our standard quality control includes comprehensive analytical techniques such as HPLC, NMR, and optical rotation measurement. A Certificate of Analysis (COA) detailing purity, chiral excess, and identity is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.