Description

Lavendustin A CAS NO 125697-92-9 is a potent and selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. This compound matters for researchers as a critical tool for studying signal transduction pathways involved in cell proliferation, differentiation, and oncogenesis. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on cancer research and kinase inhibitor development.

Application

• Biochemical Research: A key reagent for investigating EGFR-mediated signaling cascades and cellular responses.
• Cancer Research: Used in vitro to study the role of EGFR tyrosine kinase in tumor cell growth and to screen for synergistic anti-cancer agents.
• Kinase Profiling: Serves as a reference standard in selectivity panels to assess the specificity of novel kinase inhibitors.
• Signal Transduction Studies: Employed to elucidate downstream effects of EGFR inhibition on pathways like MAPK/ERK and PI3K/Akt.
• Drug Discovery: Acts as a pharmacological tool and a structural template in the design and development of new tyrosine kinase inhibitors.
• Cellular Mechanism Analysis: Used to modulate EGFR activity to understand its function in specific cell types and disease models.

Basic Information

Product Name	Lavendustin A
CAS No.	125697-92-9
Molecular Formula	C₂₀H₁₈N₂O₅
Molecular Weight	366.37 g/mol
Synonyms	Lavendustin A; NSC 677512; EGFR Tyrosine Kinase Inhibitor; 5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic Acid; 2-Hydroxy-5-[[(2-hydroxy-5-nitrophenyl)methyl][(2-hydroxyphenyl)methyl]amino]benzoic Acid (related structure); EGFR Inhibitor I; Tyrosine Kinase Inhibitor (Lavendustin A)
EINECS	Contact for details

Quality Control

Our Lavendustin A is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. The compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.