Description

Spiro[2.3]Hexane-1-Carboxylic Acid, 5-Methylene-, Methyl Ester (9Ci) is a specialized spirocyclic organic compound with the CAS number 125642-98-0, serving as a valuable synthetic intermediate in advanced organic chemistry. Its unique spiro[2.3]hexane scaffold makes it a critical building block for constructing complex molecular architectures with precise three-dimensional control. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring constrained, spirocyclic frameworks for enhanced biological activity and metabolic stability.
• Agrochemical Synthesis: Building block for developing new-generation pesticides and herbicides with unique modes of action derived from its strained ring system.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials where the spiro structure imparts specific physical or optical properties.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes and tools to study biological processes and enzyme mechanisms.
• Asymmetric Catalysis Ligand Precursor: Potential starting material for synthesizing chiral ligands used in enantioselective catalytic reactions.
• Academic & Industrial R&D: Fundamental research compound for exploring new synthetic methodologies and reaction pathways involving strained carbocycles.

Basic Information

Product Name	Spiro[2.3]Hexane-1-Carboxylic Acid, 5-Methylene-, Methyl Ester (9Ci)
CAS No.	125642-98-0
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	5-Methylenespiro[2.3]hexane-1-carboxylic acid methyl ester; Methyl 5-methylenespiro[2.3]hexane-1-carboxylate; Spiro[2.3]hexane-1-carboxylic acid, 5-methylene-, methyl ester; 1-Carbomethoxy-5-methylenespiro[2.3]hexane; Methyl 5-methylidene-1-spiro[2.3]hexanecarboxylate
EINECS	Contact for details

Quality Control

Our Spiro[2.3]Hexane-1-Carboxylic Acid, 5-Methylene-, Methyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.