Description

3-Pyrrolidinecarboxylicacid,5-(Hydroxymethyl)-,Methylester(9Ci) is a high-purity pyrrolidine derivative, a versatile chiral building block critical for advanced organic synthesis. Its value lies in its functionalized structure, which serves as a key intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific stereochemical configurations.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in the design and synthesis of peptidomimetic compounds for medicinal chemistry applications.
• Fine Chemical Production: A valuable intermediate for manufacturing specialty and custom fine chemicals with high added value.
• Academic and R&D: Used in university and corporate research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	3-Pyrrolidinecarboxylicacid,5-(Hydroxymethyl)-,Methylester(9Ci)
CAS No.	125629-87-0
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	Methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate; (3R,5R)-5-(Hydroxymethyl)pyrrolidine-3-carboxylic acid methyl ester; 5-Hydroxymethyl-3-pyrrolidinecarboxylic acid methyl ester; (3R,5R)-Methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate; Pyrrolidine-3-carboxylic acid, 5-(hydroxymethyl)-, methyl ester; (3R,5R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-(hydroxymethyl)pyrrolidine-3-carboxylic acid methyl ester (precursor form); Fmoc-protected derivative precursor
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarboxylicacid,5-(Hydroxymethyl)-,Methylester(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.