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(6-Formyl-2,2-Dimethyl-[1,3]Dioxan-4-Yl)-Acetic Acid tert-Butyl Ester CAS NO 125517-63-7


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CAS No.:125517-63-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(6-Formyl-2,2-Dimethyl-[1,3]Dioxan-4-Yl)-Acetic Acid tert-Butyl Ester is a high-value, protected aldehyde derivative and a key chiral building block in advanced organic synthesis. Its core value proposition lies in its role as a versatile intermediate for constructing complex molecules with precise stereochemistry, crucial for pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the pharmaceutical, fine chemical, and agrochemical industries who require reliable, high-purity intermediates for developing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

  • Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, anti-inflammatory, and cardiovascular therapeutic areas.
  • Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
  • Fine Chemical Production: Serves as a building block for creating specialty chemicals, flavors, and fragrances that demand high enantiomeric purity.
  • Academic & Contract Research: A valuable reagent for methodology development and asymmetric synthesis in academic laboratories and CROs (Contract Research Organizations).
  • Peptide Mimetics & Prodrug Development: The protected aldehyde and ester functionalities make it suitable for constructing peptide analogs and prodrug linkers.

Basic Information

Product Name (6-Formyl-2,2-Dimethyl-[1,3]Dioxan-4-Yl)-Acetic Acid tert-Butyl Ester
CAS No. 125517-63-7
Molecular Formula C13H22O5
Molecular Weight 258.31 g/mol
Synonyms tert-Butyl (6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate; 4-(2-tert-Butoxy-2-oxoethyl)-2,2-dimethyl-1,3-dioxane-6-carbaldehyde; (6-Formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid tert-butyl ester; Acetic acid, (6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)-, 1,1-dimethylethyl ester; Protected glyceraldehyde acetonide tert-butyl ester derivative
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Quality Control

Our (6-Formyl-2,2-Dimethyl-[1,3]Dioxan-4-Yl)-Acetic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and should be handled under inert atmosphere for long-term storage to maintain stability.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or low-melting solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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