Description

Cyclobutanecarboxylic Acid, 1-Amino-, Phenylmethyl Ester (9Ci) is a specialized organic building block featuring a cyclobutane ring system with both amino and ester functional groups. This compound is valued for its unique steric and electronic properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the cyclobutane scaffold can contribute to unique biological activity and environmental profiles.
• Material Science: Serves as a precursor for specialty polymers and advanced materials requiring rigid, cyclic structures to modify thermal and mechanical properties.
• Chemical Synthesis: A versatile reagent for constructing complex, strained-ring systems in academic and industrial organic synthesis laboratories.
• Peptidomimetics: The amino acid derivative structure makes it suitable for creating conformationally restricted peptide analogs in biochemical research.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1-Amino-, Phenylmethyl Ester (9Ci)
CAS No.	125483-56-9
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	Benzyl 1-aminocyclobutanecarboxylate; 1-Aminocyclobutanecarboxylic Acid Benzyl Ester; 1-Amino-cyclobutanecarboxylic Acid Phenylmethyl Ester; ACBC Benzyl Ester; (1-Aminocyclobutyl)carboxylic Acid Benzyl Ester; Benzyl (1-aminocyclobutane)carboxylate; 1-Amino-cyclobutanecarboxylic Acid Benzyl Ester; 125483-56-9
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 1-Amino-, Phenylmethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.