Description

1,4-Dioxaspiro[4.4]Nonane, 7,8-Bis(Methylene)- is a specialized spirocyclic compound featuring a unique dioxolane ring fused to a cyclopentane core with exocyclic methylene groups. This distinct molecular architecture makes it a valuable high-purity intermediate for synthesizing complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, fragrances, and functional materials where precise stereochemistry and functional group manipulation are critical.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those requiring spirocyclic or bridged ring systems.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive methylene groups for further functionalization.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including advanced ligands for catalysis and chiral auxiliaries.
• Fragrance and Flavor Chemistry: Employed as an intermediate for creating complex, musky, or woody odorant molecules due to its bicyclic structure.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including ring-opening and cycloaddition reactions.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Nonane, 7,8-Bis(Methylene)-
CAS No.	125404-49-1
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	7,8-Bis(methylene)-1,4-dioxaspiro[4.4]nonane; 1,4-Dioxaspiro[4.4]non-7-ene, 8-methylene-; Spiro[1,3-dioxolane-2,1'-cyclopentane], 3',4'-bis(methylene)-; 3',4'-Bis(methylene)spiro[1,3-dioxolane-2,1'-cyclopentane]; 7,8-Dimethylene-1,4-dioxaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

We supply 1,4-Dioxaspiro[4.4]Nonane, 7,8-Bis(Methylene)- in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to a cGMP-compliant quality management system for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.