Description

Spiro[Cyclopropane-1,5'-[5H]Inden]-7'(6'H)-One,6'-Hydroxy-2',4',6'-Trimethyl-, (6'R)- is a complex, chiral spirocyclic compound that serves as a sophisticated synthetic intermediate. Its defined stereochemistry and unique molecular architecture make it a valuable building block for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty chemicals. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors who require precise, structurally complex starting materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new, high-efficacy pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Material Science: Potential monomer or precursor for the synthesis of specialty polymers with unique optical or structural properties.
• Academic & Industrial R&D: Serves as a critical reagent for methodological development and exploration of new chemical spaces in organic chemistry.

Basic Information

Product Name	Spiro[Cyclopropane-1,5'-[5H]Inden]-7'(6'H)-One,6'-Hydroxy-2',4',6'-Trimethyl-, (6'R)-
CAS No.	125392-76-9
Molecular Formula	C15H18O2
Molecular Weight	230.30 g/mol
Synonyms	(6'R)-6'-Hydroxy-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one; (6R)-6-Hydroxy-2,4,6-trimethylspiro[cyclopropane-1,5-inden]-7(6H)-one; 6'-Hydroxy-2',4',6'-trimethylspiro[cyclopropane-1,5'-inden]-7'(6'H)-one, (6'R)-; Spiro[cyclopropane-1,5'-inden]-7'(6'H)-one, 6'-hydroxy-2',4',6'-trimethyl-, (6'R)-; 125392-76-9; (6R)-6-Hydroxy-2,4,6-trimethyl-1-oxaspiro[2.5]oct-4-en-8-one (alternative fused representation).
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral chromatography, GC, and NMR to confirm identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.