Description

Poly(Oxy-1,2-Ethanediyl),α-(1-Oxo-2-Propenyl)-ω-H is a functionalized polyethylene glycol (PEG) derivative, specifically a PEG-acrylate, characterized by a reactive vinyl end-group. This compound is a crucial building block in polymer chemistry, enabling the synthesis of advanced, customizable materials with tailored properties. It is essential for researchers and manufacturers in the pharmaceutical, biomedical, and specialty polymer industries who require precise macromolecular architecture for applications ranging from drug delivery to advanced coatings.

Application

• Pharmaceutical Conjugation: As a linker or spacer for PEGylating peptides, proteins, and small molecule drugs to improve solubility, stability, and circulation time.
• Hydrogel Synthesis: A key monomer for creating cross-linked, biocompatible hydrogels used in tissue engineering scaffolds, wound dressings, and contact lenses.
• Surface Modification: Crafting non-fouling, hydrophilic surfaces on medical devices, implants, and diagnostic tools to prevent protein adsorption and bacterial adhesion.
• Functional Polymer Backbone: Serving as a macromonomer for synthesizing graft copolymers, comb polymers, and other complex architectures with precise functionality.
• Bioconjugation & Diagnostics: Facilitating the attachment of biomarkers, fluorescent dyes, or targeting ligands to nanoparticles and other carriers for diagnostic applications.
• Advanced Material Research: Enabling the development of stimuli-responsive polymers, self-assembling nanostructures, and smart materials for controlled release systems.

Basic Information

Product Name	Poly(Oxy-1,2-Ethanediyl),α-(1-Oxo-2-Propenyl)-ω-H
CAS No.	125304-11-2
Molecular Formula	CnH2n+2On+2 (n varies by PEG chain length)
Molecular Weight	Variable (dependent on PEG chain length, e.g., 350, 550, 750 Da). Contact for details.
Synonyms	Poly(ethylene glycol) acrylate; PEG Acrylate; Acrylate-PEG; Acryloyl-PEG; Poly(ethylene glycol) monoacrylate; 2-Propenoic acid, 2-hydroxyethyl ester, homopolymer; Acrylated PEG; Poly(oxyethylene) acrylate; Methoxy PEG acrylate (if one end is methoxy-capped); Acryloyl monomethoxypolyethylene glycol
EINECS	Contact for details.

Quality Control

Our Poly(Oxy-1,2-Ethanediyl),α-(1-Oxo-2-Propenyl)-ω-H is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure consistent purity, functionality, and molecular weight distribution. Certificates of Analysis (COA) detailing key parameters such as assay, degree of acrylation, residual monomers, and polydispersity index are available upon request. We support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation. For optimal shelf life, store under an inert atmosphere (e.g., nitrogen or argon) and use promptly once opened.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (NMR/HPLC)	≥ 95% (Acrylate content)
Average Molecular Weight (GPC)	As per ordered grade (e.g., Mn 350, 550, 750)
Polydispersity Index (PDI)	≤ 1.10
Water Content (KF)	≤ 0.5%
Residual Acrylic Acid / Initiator	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.