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n-[4-(Acridin-9-Ylamino)Butyl]-4-[Bis(2-Chloroethyl)Amino]Benzamide CAS NO 125173-78-6
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CAS No.:125173-78-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[4-(Acridin-9-Ylamino)Butyl]-4-[Bis(2-Chloroethyl)Amino]Benzamide is a specialized, high-value synthetic compound designed for advanced research and development applications. This molecule is significant for its dual functional groups, combining an acridine moiety with a nitrogen mustard derivative, making it a candidate for targeted therapeutic and diagnostic studies. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in the development of novel anticancer agents, targeted drug delivery systems, and photodynamic therapy research.
Application
- Pharmaceutical Research & Development: Serves as a key intermediate or active component in the synthesis of novel anticancer compounds and targeted therapies.
- Bioconjugation & Probe Development: Used in the creation of fluorescent or therapeutic probes for cellular imaging and targeted drug delivery due to its acridine fluorophore and alkylating group.
- Anticancer Agent Studies: Investigated for its potential cytotoxic and DNA-intercalating properties in experimental oncology research.
- Academic & Institutional Research: Employed in chemical biology and medicinal chemistry programs to study structure-activity relationships (SAR) of bifunctional molecules.
- Preclinical Development: Utilized in the early-stage development of new chemical entities (NCEs) for various oncological targets.
Basic Information
| Product Name | n-[4-(Acridin-9-Ylamino)Butyl]-4-[Bis(2-Chloroethyl)Amino]Benzamide |
| CAS No. | 125173-78-6 |
| Molecular Formula | C30H33Cl2N5O |
| Molecular Weight | 550.52 g/mol |
| Synonyms | 4-[Bis(2-chloroethyl)amino]-N-[4-(9-acridinylamino)butyl]benzamide; NSC 687492; Acridine mustard benzamide derivative; 9-[[4-[[[4-[Bis(2-chloroethyl)amino]benzoyl]amino]butyl]amino]acridine; N-(4-(Acridin-9-ylamino)butyl)-4-(bis(2-chloroethyl)amino)benzamide |
| EINECS | Contact for details |
Quality Control
Our production of n-[4-(Acridin-9-Ylamino)Butyl]-4-[Bis(2-Chloroethyl)Amino]Benzamide adheres to stringent quality protocols suitable for research-grade materials. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as HPLC purity, NMR confirmation, and residual solvent analysis are provided with every shipment to support your critical research and development work.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area, away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellow to orange solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 95.0% |
| Related Substances (HPLC) | ≤ 5.0% total |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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