Description

n-[6-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Hexyl]Acridin-9-Amine CAS NO 125173-75-3 is a specialized nitrogen mustard derivative of acridine, designed for targeted research and development applications. This compound is valued for its unique molecular architecture, which combines a DNA-intercalating acridine moiety with a bifunctional alkylating agent, enabling precise biochemical interactions. It is primarily utilized by pharmaceutical researchers, medicinal chemists, and academic institutions engaged in the development of novel therapeutic agents and advanced biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of potential anti-cancer agents and targeted therapies.
• Biochemical Research: Used as a model compound in studies of DNA alkylation, intercalation, and the mechanisms of cell cycle inhibition.
• Medicinal Chemistry: A key precursor for the development of novel small molecules targeting specific enzymatic pathways or cellular receptors.
• Academic & Institutional R&D: Employed in university and government laboratory settings for fundamental research in chemical biology and drug discovery.
• High-Purity Reference Standard: Supplied as a characterized compound for analytical method development, validation, and quality control in research settings.

Basic Information

Item	Details
Product Name	n-[6-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Hexyl]Acridin-9-Amine
CAS No.	125173-75-3
Molecular Formula	C29H33Cl2N3
Molecular Weight	486.50 g/mol
Synonyms	9-Amino-N-[6-[4-[bis(2-chloroethyl)amino]phenyl]hexyl]acridine; Acridine mustard derivative; 1-[6-[4-[Bis(2-chloroethyl)amino]phenyl]hexyl]acridin-9-amine; Nitrogen mustard-acridine hybrid; DNA intercalator-alkylator conjugate
EINECS	Contact for details

Quality Control

Every batch of n-[6-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Hexyl]Acridin-9-Amine is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.