Description

Fmoc-D-Ala-Opfp is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled and efficient incorporation of D-alanine into peptide chains while preventing unwanted side reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes. Its reliable performance is fundamental for advancing projects in medicinal chemistry and biotechnology.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the sequential coupling of D-alanine in automated and manual peptide synthesis.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including antimicrobial peptides and hormone analogs.
• Peptidomimetic Design: Facilitates the creation of stable, non-natural peptide structures with enhanced biological activity and metabolic stability.
• Bioconjugation and Probe Synthesis: Acts as a precursor for labeling peptides with fluorophores or other reporter molecules for diagnostic and imaging applications.
• Academic Research: Employed in biochemistry and organic chemistry laboratories for studying peptide structure, function, and synthesis methodologies.
• Production of Custom Peptides: Essential for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke peptide manufacturing services.

Basic Information

Product Name	Fmoc-D-Ala-Opfp
CAS No.	125043-04-1
Molecular Formula	C24H16F5NO4
Molecular Weight	477.38 g/mol
Synonyms	Fmoc-D-alanine pentafluorophenyl ester; N-(9-Fluorenylmethoxycarbonyl)-D-alanine pentafluorophenyl ester; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid 2,3,4,5,6-pentafluorophenyl ester; D-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,3,4,5,6-pentafluorophenyl ester; Fmoc-D-Ala-OPfp; Fmoc-D-Ala-OPh(2,3,4,5,6-F5)
EINECS	Contact for details

Quality Control

Our Fmoc-D-Ala-Opfp is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive peptide synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards to support our customers' research and development needs in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.