Description

Diethyl (n-Methoxy-n-Methylcarbamoylmethyl)Phosphonate is a specialized organophosphorus compound, specifically a phosphonate ester derivative, that serves as a crucial synthetic intermediate in advanced organic synthesis. Its primary value lies in its role as a Horner-Wadsworth-Emmons (HWE) reagent, enabling the efficient and stereoselective construction of complex molecules. This chemical is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), novel drug candidates, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring olefination reactions.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Employed as a versatile reagent for the stereoselective formation of carbon-carbon double bonds in complex organic molecules.
• Academic & Industrial R&D: A valuable tool for chemists in laboratory-scale research and process development for new chemical entities.
• Material Science Precursor: Potential use in the synthesis of specialized ligands, functionalized polymers, or advanced materials.

Basic Information

Product Name	Diethyl (n-Methoxy-n-Methylcarbamoylmethyl)Phosphonate
CAS No.	124931-12-0
Molecular Formula	C10H22NO5P
Molecular Weight	267.26 g/mol
Synonyms	Diethyl (Methoxy(methyl)carbamoyl)methylphosphonate; (Methoxy(methyl)carbamoyl)methylphosphonic Acid Diethyl Ester; Diethyl [(Methoxy(methyl)amino)oxomethyl]methylphosphonate; Diethyl (N-Methoxy-N-methylcarbamoylmethyl)phosphonate; HWE Reagent Derivative; Phosphonoacetic Acid, (N-Methoxy-N-methylamide), Diethyl Ester; Weiler's Reagent Analog; (Carbamoylmethyl)phosphonate Ester
EINECS	Contact for details

Quality Control

Our Diethyl (n-Methoxy-n-Methylcarbamoylmethyl)Phosphonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.