Description

2,5,6-Trimethoxynicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic positioning of its aldehyde and methoxy groups, which enable precise chemical transformations for building complex molecular architectures. This compound is essential for research chemists and process developers in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators due to its bioactive pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as conductive polymers and light-emitting compounds.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A high-value starting material for custom synthesis projects requiring specific, multi-functionalized heterocycles.

Basic Information

Product Name	2,5,6-Trimethoxynicotinaldehyde
CAS No.	124769-08-0
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	Nicotinaldehyde, 2,5,6-trimethoxy-; 2,5,6-Trimethoxy-3-pyridinecarboxaldehyde; 3-Formyl-2,5,6-trimethoxypyridine; 2,5,6-Trimethoxypyridine-3-carbaldehyde; Pyridine-3-carboxaldehyde, 2,5,6-trimethoxy-
EINECS	Contact for details

Quality Control

Every batch of 2,5,6-Trimethoxynicotinaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.