Description

6-o-(tert-Butyldimethylsilyl)-D-Galactal is a high-purity, protected carbohydrate derivative, specifically a silyl ether of D-galactal, serving as a crucial chiral building block in advanced organic synthesis. Its primary value lies in providing a reactive glycosyl donor intermediate with a protected hydroxyl group, enabling precise and selective glycosylation reactions under controlled conditions. This compound is essential for researchers and process chemists in the pharmaceutical, biotechnology, and fine chemical industries, particularly for the development of complex glycoconjugates, oligosaccharides, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of nucleoside analogs, glycomimetics, and other bioactive molecules.
• Glycochemistry Research: Used as a protected glycosyl donor in the study and construction of complex oligosaccharides and glycoconjugates.
• Process Chemistry: Enables scalable, stereoselective glycosylation steps in the production of active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry: Fundamental building block for modifying sugar moieties and exploring new synthetic pathways in carbohydrate-based chemistry.
• Bioconjugation: Facilitates the site-specific attachment of carbohydrate structures to proteins, lipids, or other biomolecules for diagnostic and therapeutic applications.
• Standards & Reference Materials: Serves as a high-purity analytical standard for method development and quality control in related chemical processes.

Basic Information

Product Name	6-o-(tert-Butyldimethylsilyl)-D-Galactal
CAS No.	124751-19-5
Molecular Formula	C₁₂H₂₄O₅Si
Molecular Weight	276.41 g/mol
Synonyms	D-Galactal, 6-O-[(1,1-Dimethylethyl)dimethylsilyl]-; 6-O-TBDMS-D-Galactal; 6-O-(tert-Butyldimethylsilyl)-1,5-anhydro-2-deoxy-D-lyxo-hex-1-enitol; 1,5-Anhydro-2-deoxy-6-O-[(1,1-dimethylethyl)dimethylsilyl]-D-lyxo-hex-1-enitol; TBDMS-D-Galactal; tert-Butyldimethylsilyl D-galactal ether
EINECS	Contact for details

Quality Control

Our 6-o-(tert-Butyldimethylsilyl)-D-Galactal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research and cGMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines for stability and impurity characterization, ensuring the material meets the exacting standards required for synthetic chemistry and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali. Keep away from incompatible materials and moisture. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.