Description

Benzeneacetic Acid, A-Amino-, 1,1-Dimethylethyl Ester . Hcl is a protected amino acid derivative, specifically the tert-butyl ester hydrochloride salt of phenylglycine. This compound is a crucial chiral building block in organic synthesis, valued for its role in introducing the phenylglycine moiety while protecting the carboxylic acid functionality. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for the production of active pharmaceutical ingredients (APIs), peptides, and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of various APIs, including antibiotics, enzyme inhibitors, and cardiovascular drugs.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry to construct peptide chains.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Labeling: Utilized in the preparation of modified biomolecules for diagnostic and research applications.
• Academic & Industrial R&D: Fundamental building block in medicinal chemistry and process development laboratories for novel compound libraries.

Basic Information

Product Name	Benzeneacetic Acid, A-Amino-, 1,1-Dimethylethyl Ester . Hcl
CAS No.	124619-74-5
Molecular Formula	C₁₂H₁₈ClNO₂
Molecular Weight	243.73 g/mol
Synonyms	(±)-2-Amino-2-phenylacetic acid tert-butyl ester hydrochloride; DL-Phenylglycine tert-butyl ester hydrochloride; tert-Butyl 2-amino-2-phenylacetate hydrochloride; 2-Phenylglycine tert-butyl ester HCl; Amino(phenyl)acetic acid 1,1-dimethylethyl ester hydrochloride; Phenylglycine t-butyl ester hydrochloride; Boc-Phenylglycine-OH?HCl (Note: This is a common misnomer, as the protecting group is t-butyl, not Boc); (RS)-2-Amino-2-phenylacetic acid t-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, A-Amino-, 1,1-Dimethylethyl Ester . Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.