Description

Cyclopentanecarboxylic Acid, 2-Hydroxy-, Methyl Ester, (1S,2R)- (9Ci) is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry at the 1S and 2R positions makes it a valuable precursor for the production of complex, optically active molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries, where it serves as a key synthon for active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Used as a starting material or advanced intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of new, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require specific stereoisomers.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and for studying structure-activity relationships (SAR).
• Ligand and Catalyst Synthesis: Can be utilized to create novel chiral ligands or organocatalysts for use in enantioselective transformations.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Hydroxy-, Methyl Ester, (1S,2R)- (9Ci)
CAS No.	124150-23-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(1S,2R)-2-Hydroxycyclopentanecarboxylic Acid Methyl Ester; Methyl (1S,2R)-2-Hydroxycyclopentanecarboxylate; (1S,2R)-Methyl 2-Hydroxycyclopentanecarboxylate; trans-(1S,2R)-Methyl 2-Hydroxycyclopentanecarboxylate; L-erythro-2-Hydroxycyclopentanecarboxylic Acid Methyl Ester; Optically Active Methyl 2-Hydroxycyclopentanecarboxylate; Chiral Cyclopentane Derivative; CAS 124150-23-8
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Hydroxy-, Methyl Ester, (1S,2R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.