Description

Dihydroartemisinin is a potent, semi-synthetic derivative of artemisinin, a naturally occurring sesquiterpene lactone. This compound serves as a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of more complex artemisinin-based antimalarial drugs. It is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of advanced antimalarial therapies. Dihydroartemisinin CAS NO 123930-80-3 represents a cornerstone in the global fight against malaria, particularly in regions with drug-resistant strains.

Application

• Active Pharmaceutical Ingredient (API): Primary use as the core component in the formulation of artemisinin-based combination therapies (ACTs) for the treatment of Plasmodium falciparum malaria.
• Pharmaceutical Intermediate: Key synthetic precursor for the production of artemisinin derivatives such as artemether, artesunate, and arteether.
• Research & Development: Used in pharmacological and biochemical research to study antimalarial mechanisms of action, drug resistance, and new therapeutic applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and assay validation in pharmaceutical laboratories.
• Veterinary Medicine: Investigated for potential applications in treating parasitic infections in animals.

Basic Information

Product Name	Dihydroartemisinin
CAS No.	123930-80-3
Molecular Formula	C15H24O5
Molecular Weight	284.35 g/mol
Synonyms	Artenimol; Dihydroqinghaosu; DHA; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; Dihydro-artemisinin; Arteannuin B
EINECS	Contact for details

Quality Control

Our Dihydroartemisinin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and specific tests for related substances and residual solvents, to ensure compliance with pharmaceutical-grade standards. We support our commitment to quality with readily available Certificates of Analysis (COA), which detail all specifications and test results. Our processes are designed to meet the rigorous demands of API production and global regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere (e.g., nitrogen) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.