Description

D-Ribo-Hexonic Acid, 3-Deoxy-6-o-(1,1-Dimethylethyl)Dimethylsilyl-4-o-(Phenylmethyl)-2-o-2-Propenyl-, .Delta.-Lactone is a sophisticated, multi-protected sugar lactone derivative, a key chiral building block in advanced organic synthesis. This compound is valued for its precise stereochemistry and functional group arrangement, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs), nucleoside analogs, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of complex drug candidates, particularly nucleoside-based therapeutics and antiviral agents.
• Glycochemistry Research: Used as a protected sugar derivative for studying glycosylation reactions and synthesizing complex oligosaccharides or glycomimetics.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value specialty chemicals.
• Asymmetric Synthesis: Acts as a chiral pool starting material or auxiliary for constructing stereocenters in natural product synthesis and catalyst development.
• Chemical Biology Probes: Utilized in the design and synthesis of labeled sugar analogs or molecular probes for biological mechanism studies.

Basic Information

Item	Details
Product Name	D-Ribo-Hexonic Acid, 3-Deoxy-6-o-(1,1-Dimethylethyl)Dimethylsilyl-4-o-(Phenylmethyl)-2-o-2-Propenyl-, .Delta.-Lactone
CAS No.	123920-17-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-Deoxy-6-O-(tert-butyldimethylsilyl)-4-O-benzyl-2-O-allyl-D-ribo-hexono-1,5-lactone; 6-O-TBDMS-4-O-Bn-2-O-allyl-3-deoxy-D-ribo-hexonolactone; 3-Deoxy-6-O-TBDMS-4-O-Bzl-2-O-allyl-D-ribo-hexono-1,5-lactone; Protected D-ribo-hexonolactone derivative; TBDMS/Bn/allyl-protected sugar lactone; CAS 123920-17-2
EINECS	Contact for details

Quality Control

Every batch of this advanced synthetic intermediate is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality systems are designed to support cGMP requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Keep away from incompatible materials such as fluorides and strong alkali.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.