Description

Cyclopropanecarboxylic Acid, 1-Amino-2-Phenyl-, Methyl Ester, (1R-Trans)- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its stereochemically defined cyclopropane and amino ester functional groups, which are key building blocks in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel APIs, particularly in central nervous system (CNS) and antiviral drug research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with specific stereochemical activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective reactions.
• Peptidomimetic Chemistry: Incorporated into the design of peptide analogs and conformationally restricted scaffolds for drug discovery.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with unique structural properties.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-Phenyl-, Methyl Ester, (1R-Trans)-
CAS No.	123806-63-3
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	(1R,2S)-1-Amino-2-phenylcyclopropanecarboxylic acid methyl ester; Methyl (1R,2S)-1-amino-2-phenylcyclopropanecarboxylate; (1R-trans)-1-Amino-2-phenylcyclopropanecarboxylic Acid Methyl Ester; trans-(1R,2S)-1-Amino-2-phenylcyclopropanecarboxylic acid methyl ester; (1R,2S)-1-Amino-2-phenylcyclopropanecarboxylic acid methyl ester; (1R,2S)-Amino phenylcyclopropane carboxylate methyl ester; Methyl (1R,2S)-1-amino-2-phenylcyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-Phenyl-, Methyl Ester, (1R-Trans)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.