Description

2,4-Dinitrophenyl-4-o-(4,4'-Dimethoxytrityl)Butyrate is a specialized chemical intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex molecules, particularly in oligonucleotide and nucleoside chemistry. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, diagnostics, and high-value fine chemicals.

Application

• Oligonucleotide Synthesis: A critical reagent in solid-phase phosphoramidite chemistry for the controlled assembly of DNA and RNA strands.
• Nucleoside & Nucleotide Chemistry: Used in the protection and functionalization of nucleosides during the synthesis of modified nucleotides.
• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of antiviral and anticancer prodrugs.
• Bioconjugation: Employed in the labeling and modification of biomolecules for diagnostic and research applications.
• Protecting Group Chemistry: Utilizes the dimethoxytrityl (DMT) group for the selective protection of hydroxyl functions in multi-step syntheses.
• Academic & Industrial R&D: A valuable tool for chemists exploring novel synthetic pathways and molecular architectures.

Basic Information

Product Name	2,4-Dinitrophenyl-4-o-(4,4'-Dimethoxytrityl)Butyrate
CAS No.	123658-23-1
Molecular Formula	C33H32N2O8
Molecular Weight	584.62 g/mol
Synonyms	4-[(4,4'-Dimethoxytrityl)oxy]butyric Acid 2,4-Dinitrophenyl Ester; DMT-ONp Ester; 4-O-(4,4'-Dimethoxytrityl)butyric Acid 2,4-Dinitrophenyl Ester; DNP-DMT-Ester; 2,4-DNP-DMT-Ester; 4-(Dimethoxytrityloxy)butyric Acid Dinitrophenyl Ester; Oligonucleotide Synthesis Reagent DMT-ONp
EINECS	Contact for details

Quality Control

Our 2,4-Dinitrophenyl-4-o-(4,4'-Dimethoxytrityl)Butyrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.