Description

n-Benzyl-L-Serine, Methyl Ester is a protected amino acid derivative of significant importance in synthetic organic and medicinal chemistry. This compound serves as a crucial chiral building block for the synthesis of complex peptides, peptidomimetics, and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development, where high-purity, enantiomerically pure intermediates are essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic peptides and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis where the benzyl and methyl ester groups offer orthogonal protection for the serine side chain and carboxyl group, respectively.
• Chemical Biology Research: Employed in the design and construction of modified amino acids and peptide-based probes for studying biological mechanisms.
• Ligand and Catalyst Development: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Serves as a standard or starting material in research laboratories for method development and exploratory chemistry.

Basic Information

Product Name	n-Benzyl-L-Serine, Methyl Ester
CAS No.	123639-56-5
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	L-Serine, N-benzyl-, methyl ester; Methyl N-benzyl-L-serinate; (2S)-2-(Benzylamino)-3-hydroxypropanoic acid methyl ester; N-Benzyl-O-serine methyl ester; Serine, N-benzyl-, methyl ester, L-; Benzylserine methyl ester; Methyl (S)-2-(benzylamino)-3-hydroxypropanoate
EINECS	Contact for details

Quality Control

Our n-Benzyl-L-Serine, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.