Description

(1S,2R)-1-Phenyl-2-(1-Pyrrolidinyl)Propan-1-Ol is a chiral organic compound featuring a phenyl and pyrrolidine moiety, making it a valuable intermediate in asymmetric synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where its defined stereochemistry is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of various therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug research.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure pesticides and herbicides.
• Academic & Industrial Research: A standard compound for methodological studies in organic chemistry, including novel C-C and C-N bond-forming reactions.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemical configurations.

Basic Information

Product Name	(1S,2R)-1-Phenyl-2-(1-Pyrrolidinyl)Propan-1-Ol
CAS No.	123620-80-4
Molecular Formula	C₁₃H₁₉NO
Molecular Weight	205.30 g/mol
Synonyms	(1S,2R)-1-Phenyl-2-(pyrrolidin-1-yl)propan-1-ol; (1S,2R)-1-Phenyl-2-(1-pyrrolidinyl)-1-propanol; (-)-(1S,2R)-1-Phenyl-2-(1-pyrrolidinyl)propan-1-ol; L-Phenylpropanolamine pyrrolidine derivative; (1S,2R)-Norephedrine pyrrolidine adduct; (1S,2R)-1-Phenyl-2-pyrrolidin-1-ylpropan-1-ol
EINECS	Contact for details

Quality Control

Our (1S,2R)-1-Phenyl-2-(1-Pyrrolidinyl)Propan-1-Ol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.