Description

2-Aziridinecarboxylicacid,1-Acetyl-,Methylester,(1R-Trans)-(9Ci) is a high-purity, chiral aziridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its stereochemically defined, strained three-membered ring structure, which is essential for constructing complex molecules with high precision. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, anticancer agents, and other biologically active molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Peptidomimetics & Drug Discovery: Serves as a constrained amino acid analog for creating peptide-like compounds with enhanced metabolic stability and binding affinity.
• Polymer Science: Acts as a monomer or cross-linking agent for producing specialty polymers with unique mechanical or chemical properties.
• Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective ring-opening reactions and nucleophilic additions.
• Chemical Biology Probes: Utilized in the design of activity-based probes and molecular tools for studying enzyme mechanisms.

Basic Information

Product Name	2-Aziridinecarboxylicacid,1-Acetyl-,Methylester,(1R-Trans)-(9Ci)
CAS No.	123557-03-9
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	(1R,2S)-1-Acetyl-2-carbomethoxyaziridine; Methyl (1R,2S)-1-acetylaziridine-2-carboxylate; (1R-trans)-1-Acetylaziridine-2-carboxylic Acid Methyl Ester; trans-Methyl 1-acetylaziridine-2-carboxylate; Aziridine-2-carboxylic acid, 1-acetyl-, methyl ester, (1R-trans)-; (1R,2S)-rel-1-Acetyl-2-(methoxycarbonyl)aziridine
EINECS	Contact for details

Quality Control

Our 2-Aziridinecarboxylicacid,1-Acetyl-,Methylester,(1R-Trans)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.