Description

4-(Maleinimido)Phenyl Isocyanate is a highly reactive bifunctional compound that combines a maleimide group with a phenyl isocyanate moiety. This dual functionality makes it a critical building block for creating advanced polymers and cross-linked materials with tailored properties. It is primarily sought after by researchers and manufacturers in the pharmaceutical, advanced materials, and specialty polymer sectors for applications requiring precise molecular conjugation and stable network formation.

Application

• Pharmaceutical Conjugation: A key linker for attaching drug molecules, peptides, or targeting ligands to carrier proteins, antibodies, or nanoparticles via thiol-maleimide and amine-isocyanate chemistries.
• Advanced Polymer Synthesis: Serves as a cross-linking agent and monomer for producing polyurethanes, polyureas, and other specialty polymers with enhanced thermal and mechanical stability.
• Surface Modification: Used to functionalize surfaces (e.g., glass, metals, polymers) with maleimide groups, enabling subsequent bioconjugation for biosensors, diagnostic assays, and lab-on-a-chip devices.
• Hydrogel Fabrication: Employed in the synthesis of cross-linked hydrogel networks for controlled drug delivery systems, tissue engineering scaffolds, and wound dressings.
• Adhesive & Coating Formulations: Imparts improved adhesion, chemical resistance, and durability to high-performance coatings, sealants, and composite materials.
• Material Science Research: A valuable reagent for developing novel dendritic polymers, star polymers, and other complex macromolecular architectures with precise functionality.

Basic Information

Product Name	4-(Maleinimido)Phenyl Isocyanate
CAS No.	123457-83-0
Molecular Formula	C11H6N2O3
Molecular Weight	214.18 g/mol
Synonyms	4-Isocyanatophenyl maleimide; 1-Isocyanato-4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)benzene; 4-Maleimidophenyl isocyanate; Maleimidophenyl isocyanate; N-(4-Isocyanatophenyl)maleimide; p-Maleimidophenyl isocyanate; MPI; 4-MPI
EINECS	Contact for details

Quality Control

Every batch of 4-(Maleinimido)Phenyl Isocyanate is subjected to rigorous analytical testing to ensure high purity and consistent performance. Our quality assurance protocols are designed to meet the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its moisture-sensitive (hygroscopic) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.