Description

Methyl 6-Hydroxy-2-Hexynoate is a bifunctional organic compound featuring both a terminal alkyne and a hydroxyl group, protected as a methyl ester. This unique structure makes it a versatile and valuable chemical building block for advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring alkyne functionalization for click chemistry or coupling reactions.
• Ligand and Catalyst Synthesis: Used in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Polymer Chemistry: Acts as a monomer or chain extender for creating specialty polymers with tailored properties, such as polyesters or polyurethanes with alkyne side chains for further modification.
• Material Science Research: Employed in the development of novel organic materials, including liquid crystals, dendrimers, and functional surfaces where precise molecular geometry is critical.
• Agrochemical Synthesis: Utilized as an intermediate in the research and production of advanced crop protection agents and plant growth regulators.
• Bioconjugation: The alkyne group is ideal for Huisgen cycloaddition (click chemistry) to attach fluorescent probes, drugs, or other molecules to biomolecules for diagnostic and therapeutic applications.

Basic Information

Product Name	Methyl 6-Hydroxy-2-Hexynoate
CAS No.	123368-72-9
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	6-Hydroxy-2-hexynoic acid methyl ester; Methyl 6-hydroxyhex-2-ynoate; Methyl 6-hydroxy-2-hexynoate; 2-Hexynoic acid, 6-hydroxy-, methyl ester; Methyl ester of 6-hydroxy-2-hexynoic acid
EINECS	Contact for details

Quality Control

Our Methyl 6-Hydroxy-2-Hexynoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.