Description

(2S,3S)-α2,α2,α3,α3-Tetraphenyl-1,4-Dioxaspiro[4.5]Decane-2,3-Dimethanol is a high-value, chiral spirocyclic diol compound characterized by its unique stereochemistry and multiple phenyl substituents. This compound matters as a sophisticated chiral building block and ligand, enabling precise stereocontrol in asymmetric synthesis for the production of complex molecules. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for applications in catalysis and as an intermediate for advanced active pharmaceutical ingredients (APIs).

Application

• As a chiral ligand or auxiliary in asymmetric catalysis for pharmaceutical synthesis.
• As a key chiral building block for the research and development of novel Active Pharmaceutical Ingredients (APIs).
• In the synthesis of complex natural products and other stereochemically defined fine chemicals.
• For use in methodological development in academic and industrial organic chemistry research.
• Potential application in the preparation of specialty polymers with controlled stereochemistry.
• As a reference standard for analytical method development and quality control in chiral chemistry.

Basic Information

Product Name	(2S,3S)-α2,α2,α3,α3-Tetraphenyl-1,4-Dioxaspiro[4.5]Decane-2,3-Dimethanol
CAS No.	123287-35-4
Molecular Formula	C38H36O4
Molecular Weight	556.70 g/mol
Synonyms	(2S,3S)-2,3-Bis(hydroxymethyl)-2,3,5,5-tetraphenyl-1,4-dioxaspiro[4.5]decane; (2S,3S)-Tetraphenyl-1,4-dioxaspiro[4.5]decane-2,3-dimethanol; (S,S)-Tetraphenyl-Spiroketal Diol; (S,S)-TP-SKD; Chiral Spiro Diol Ligand; (2S,3S)-TADDOL derivative; 1,4-Dioxaspiro[4.5]decane-2,3-dimethanol, 2,3,5,5-tetraphenyl-, (2S,3S)-
EINECS	Contact for details

Quality Control

Our (2S,3S)-α2,α2,α3,α3-Tetraphenyl-1,4-Dioxaspiro[4.5]Decane-2,3-Dimethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.