Description

1-(Triisopropylsilyl)Indole is a versatile organosilicon-protected indole derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a protective group for the indole nitrogen, enabling selective functionalization and complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those containing indole scaffolds.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides requiring selective protection strategies.
• Material Science Research: Building block for creating organic semiconductors, liquid crystals, and other functional organic materials.
• Academic & R&D Laboratories: Essential reagent for methodological development in organic chemistry and total synthesis projects.
• Peptide Mimetics: Facilitates the incorporation of modified tryptophan analogs into peptide chains.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki or Heck couplings for biaryl formation.

Basic Information

Product Name	1-(Triisopropylsilyl)Indole
CAS No.	123191-00-4
Molecular Formula	C17H27NSi
Molecular Weight	273.49 g/mol
Synonyms	1-Triisopropylsilylindole; N-Triisopropylsilylindole; 1H-Indole, 1-[(1,1-dimethylethyl)dimethylsilyl]-; 1-(Triisopropylsilyl)-1H-indole; TIPS-Indole; N-TIPS-indole; Indole, 1-(triisopropylsilyl)-; 1-TIPS-1H-indole
EINECS	Contact for details

Quality Control

Our 1-(Triisopropylsilyl)Indole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to meet the rigorous standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.