Description

6-Bromo-2-Pyridinecarbonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a nitrile group, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nitrile Functionalization: The cyano group can be further transformed into amides, acids, or tetrazoles, expanding its utility in medicinal chemistry.

Basic Information

Product Name	6-Bromo-2-Pyridinecarbonitrile
CAS No.	122918-25-6
Molecular Formula	C6H3BrN2
Molecular Weight	183.01 g/mol
Synonyms	2-Bromo-6-cyanopyridine; 6-Bromopicolinonitrile; 2-Cyano-6-bromopyridine; 6-Bromo-2-cyanopyridine; 6-Bromopyridine-2-carbonitrile; Picolinonitrile, 6-bromo-; (6-Bromopyridin-2-yl)methanenitrile
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.