Description

Ethyl 2-(Trifluoromethyl Sulfonyloxy)-1-Cyclohexene-1-Carboxylate is a high-value, specialized fluorinated building block used in advanced organic synthesis. This compound matters for its role as a versatile electrophilic reagent, enabling the efficient introduction of the trifluoromethanesulfonate (triflate) group into complex molecular frameworks. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of complex, fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the trifluoromethyl group enhances biological activity and environmental stability.
• Cross-Coupling Reactions: Serves as an excellent substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the reactivity of the triflate leaving group.
• Material Science Research: Employed in the synthesis of fluorinated monomers and polymers for specialty coatings, electronics, and high-performance materials.
• Organic Methodology Development: A valuable reagent for academic and industrial research focused on new fluorination techniques and C-C bond formation strategies.
• Ligand and Catalyst Preparation: Used to synthesize sophisticated fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl Sulfonyloxy)-1-Cyclohexene-1-Carboxylate
CAS No.	122135-83-5
Molecular Formula	C10H13F3O5S
Molecular Weight	302.27 g/mol
Synonyms	Ethyl 2-[(Trifluoromethyl)sulfonyloxy]-1-cyclohexene-1-carboxylate; 1-Cyclohexene-1-carboxylic acid, 2-[(trifluoromethyl)sulfonyl]oxy]-, ethyl ester; Ethyl 2-(Trifluoromethanesulfonyloxy)cyclohex-1-ene-1-carboxylate; 2-(Triflyloxy)-1-cyclohexene-1-carboxylic acid ethyl ester; Cyclohexene Triflate Ester; Trifluoromethanesulfonic acid 1-(ethoxycarbonyl)-1-cyclohexen-2-yl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl Sulfonyloxy)-1-Cyclohexene-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.