Description

n-(2-Pyridinylmethyl)-5-Oxo-L-Prolinamide is a specialized organic compound featuring a proline-derived amide structure with a pyridinylmethyl substituent. This unique molecular architecture makes it a valuable intermediate for the synthesis of more complex molecules in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors due to its proline-based scaffold, which is common in many inhibitor designs.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel pesticides or herbicides with specific activity profiles.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptidomimetics—molecules that mimic peptides—for drug discovery applications.
• Ligand for Metal Complexation: The pyridine nitrogen can act as a coordination site in the development of catalysts or metal-organic frameworks (MOFs).
• Biochemical Tool Compound: Used in academic and industrial research labs as a standard or reference material in method development and biological screening assays.

Basic Information

Product Name	n-(2-Pyridinylmethyl)-5-Oxo-L-Prolinamide
CAS No.	121873-15-2
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	5-Oxo-L-prolinamide, N-[(2-pyridinyl)methyl]-; L-Pyroglutamic acid amide, N-(2-pyridylmethyl)-; N-(Pyridin-2-ylmethyl)-5-oxopyrrolidine-2-carboxamide; (S)-N-(Pyridin-2-ylmethyl)-5-oxopyrrolidine-2-carboxamide; 2-Pyrrolidinecarboxamide, 5-oxo-N-(2-pyridinylmethyl)-, (S)-; (S)-5-Oxo-N-(pyridin-2-ylmethyl)pyrrolidine-2-carboxamide; (S)-N-(2-Pyridylmethyl)pyroglutaminamide
EINECS	Contact for details

Quality Control

Our n-(2-Pyridinylmethyl)-5-Oxo-L-Prolinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and potential degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.